Dear Friends Gene Saragnese Executive Vice President and CEO Imaging Systems, Philips Healthcare +  Read Blood-brain barrier permeability: quantification with computed tomography and application in acute ischemic stroke M. Wintermark, J. Hom, J. W. Dankbaar J. Bredno and M.E. Olszewski The costs associated with a stroke make improvements in treatment of paramount importance. Quantitative CT imaging may enable treatment based on physiology rather than time. + Read article Clinical MR tractography: past, present, and future K. Yamada, K. Akazawa, S. Yuen and T. Nishimura Diffusion tensor imaging (DTI)-based tractography was first introduced to the medical community a decade ago. Since then, the technique has been widely used in routine clinical practice in many different fields and its application is reviewed in this article. + Read article Clinical applications of diffusion tensor imaging in children N.K. Rollins and J.M. Chia DTI, a relatively new addition to Magnetic Resonance (MR) imaging, exploits the preferential movement of water protons within the brain along the axis of the axons. DTI has numerous applications in the pediatric brain from birth onwards, in normal and disease states. + Read article Functional MRI of the sensorimotor system in newborns H. Boecker, L. Scheef and A. Heep Neonatal functional MRI (fMRI) allows non-invasive in vivo mapping of dedicated brain circuits at the early stages of development. The article describes optimizing fMRI studies on infants at high risk of developing motor sequelae because of preterm birth. + Read article 7T MRI in neurology: initial results and future applications A.G. Webb, M.J. Versluis, M.A van Buchem, H.E. Kan, W.M. Teeuwisse and M.J.P. van Osch The C.J. Gorter Center for High Field MRI uses one of only two Philips Achieva 7T whole-body MRI research systems in the Netherlands to develop new methods and protocols. + Read article Dynamic whole-spine MRI of contortionists W.W. Orrison Jr. and T.G. Perkins A study of anterior limbus fractures in a group of contortionists demonstrates the ability of the Panorama HFO 1T open MR system to examine the spine in extreme positions, without the restrictions imposed by the conventional cylinder. + Read article Molecular imaging in dementia: journey to the end of the night V.L.Villemagne and G.J. O’Keefe New therapeutic strategies for dementia increase interest in developing agents to allow assessment of the pathophysiological mechanisms. A review of recent developments in molecular imaging illustrates molecular imaging utility in clinical management of dementia. + Read article Three-dimensional real-time in vivo magnetic particle imaging J. Borgert, B. Gleich, J. Rahmer, H. Dahnke and J. Weizenecker Magnetic particle imaging (MPI) is a new imaging method capable of imaging the local concentration of commercially available contrast agent with high spatial and temporal resolution. This article presents the first in vivo 3D real-time MPI scans revealing details of a beating mouse heart using clinically approved concentrations of a commercially available MRI contrast agent. + Read article 3D-multimodality roadmapping in interventional neuroradiology T. Andersson, M. Söderman, D. Ruijters, D. Babic, R. Homan and P. Mielekamp This article describes a method of fusing, in real time, 2D fluoroscopic images with 3D MRI and CT images. The resulting combined image helps to reduce the overall workload and allows for a better anatomical understanding with more precise navigation. + Read article Summaries + Read article Technology News + Read article
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